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Humoral and cellular immune responses to airway immunization of mice with human papillomavirus type 16 virus-like particles and mucosal adjuvants

✍ Scribed by Véronique Revaz; Rinaldo Zurbriggen; Christian Moser; John T. Schiller; Françoise Ponci; Martine Bobst; Denise Nardelli-Haefliger


Book ID
113457595
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
789 KB
Volume
76
Category
Article
ISSN
0166-3542

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## Abstract To develop more potent and convenient mucosal human papillomavirus (HPV) vaccines, we tested the effect of thermosensitive mucoadhesive vaginal vaccine delivery systems on the local and systemic antibody responses to HPV 16 L1 virus‐like particles (VLP). HPV 16 L1 VLP expressed from rec