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Immune responses induced by lower airway mucosal immunisation with a human papillomavirus type 16 virus-like particle vaccine

✍ Scribed by Denise Nardelli-Haefliger; Floriana Lurati; Daniel Wirthner; François Spertini; John T. Schiller; Douglas R. Lowy; Françoise Ponci; Pierre De Grandi


Book ID
116958004
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
139 KB
Volume
23
Category
Article
ISSN
0264-410X

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## Abstract To develop more potent and convenient mucosal human papillomavirus (HPV) vaccines, we tested the effect of thermosensitive mucoadhesive vaginal vaccine delivery systems on the local and systemic antibody responses to HPV 16 L1 virus‐like particles (VLP). HPV 16 L1 VLP expressed from rec