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Enhanced humoral and cellular immune responses after sublingual immunization against human papillomavirus 16 L1 protein with adjuvants

โœ Scribed by Hee-Jeong Cho; Ji-Yeon Kim; Young Lee; Jung Mogg Kim; Young Bong Kim; Taehoon Chun; Yu-Kyoung Oh


Book ID
116962387
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
816 KB
Volume
28
Category
Article
ISSN
0264-410X

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## Abstract To develop more potent and convenient mucosal human papillomavirus (HPV) vaccines, we tested the effect of thermosensitive mucoadhesive vaginal vaccine delivery systems on the local and systemic antibody responses to HPV 16 L1 virusโ€like particles (VLP). HPV 16 L1 VLP expressed from rec