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Human Telomeric DNA Sequence-Specific Cleaving by G-Quadruplex Formation

✍ Scribed by Xu, Yan; Suzuki, Yuta; Lönnberg, Tuomas; Komiyama, Makoto

Book ID
126859639
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
650 KB
Volume
131
Category
Article
ISSN
0002-7863

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## Abstract Human telomeric DNA consists of tandem repeats of the sequence 5′‐d(TTAGGG)‐3′. Guanine‐rich DNA, such as that seen at telomeres, forms G‐quadruplex secondary structures. Alternative forms of G‐quadruplex structures can have differential effects on activities involved in telomere mainte