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Molecular Recognition of Human Telomeric DNA by Phenanthroline-Based G-Quadruplex Ligands

✍ Scribed by Artese, Anna; Parrotta, Lucia; Alcaro, Stefano; Ortuso, Francesco; Costa, Giosuè; Sissi, Claudia

Book ID
120500112
Publisher
Scientific Research Publishing
Year
2013
Weight
633 KB
Volume
03
Category
Article
ISSN
2164-3121

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## Abstract Human telomeric DNA consists of tandem repeats of the sequence 5′‐d(TTAGGG)‐3′. Guanine‐rich DNA, such as that seen at telomeres, forms G‐quadruplex secondary structures. Alternative forms of G‐quadruplex structures can have differential effects on activities involved in telomere mainte