Human papillomavirus type 16 E6 inhibits p21WAF1 transcription independently of p53 by inactivating p150Sal2
✍ Scribed by Peggy Parroche; Majid Touka; Mariam Mansour; Véronique Bouvard; Amélie Thépot; Rosita Accardi; Christine Carreira; Guillaume G. Roblot; Bakary S. Sylla; Uzma Hasan; Massimo Tommasino
- Book ID
- 113948316
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 674 KB
- Volume
- 417
- Category
- Article
- ISSN
- 0042-6822
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We and others have previously reported that human papillomavirus (HPV)-16 E6 protein expression sensitizes certain cell types to apoptosis. To confirm that this sensitization occurred in HPV's natural host cells, and to explore the mechanism(s) of sensitization, we infected human keratinocytes (HKCs