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The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300

✍ Scribed by Patel, D.

Book ID
119770425
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
447 KB
Volume
18
Category
Article
ISSN
0261-4189

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Human papillomavirus type 16 E6 and HPV-
Human papillomavirus type 16 E6 and HPV-16 E6/E7 sensitize human keratinocytes to apoptosis induced by chemotherapeutic agents: Roles of p53 and caspase activation
✍ Yongmin Liu; Ann McKalip; Brian Herman πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 583 KB

We and others have previously reported that human papillomavirus (HPV)-16 E6 protein expression sensitizes certain cell types to apoptosis. To confirm that this sensitization occurred in HPV's natural host cells, and to explore the mechanism(s) of sensitization, we infected human keratinocytes (HKCs