𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human papillomavirus 16 L1–E7 chimeric virus like particles show prophylactic and therapeutic efficacy in murine model of cervical cancer

✍ Scribed by Chandresh Sharma; Bindu Dey; Mohammed Wahiduzzaman; Neeta Singh

Book ID
116965044
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1023 KB
Volume
30
Category
Article
ISSN
0264-410X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Immunization with an HPV-16 L1-based chi
Immunization with an HPV-16 L1-based chimeric virus-like particle containing HPV-16 E6 and E7 epitopes elicits long-lasting prophylactic and therapeutic efficacy in an HPV-16 tumor mice model
✍ Monroy-García, Alberto; Gómez-Lim, Miguel Angel; Weiss-Steider, Benny; Hernán 📂 Article 📅 2013 🏛 Springer Vienna 🌐 English ⚖ 709 KB

HPV L1-based virus-like particles vaccines (VLPs) efficiently induce temporary prophylactic activity through the induction of neutralizing antibodies; however, VLPs that can provide prophylactic as well as therapeutic properties for longer periods of time are needed. For this purpose, we generated a

Immune response to human papillomavirus
Immune response to human papillomavirus 16 L1E7 chimeric virus-like particles: Induction of cytotoxic T cells and specific tumor protection
✍ Klaus Schäfer; Martin Müller; Stefan Faath; Annette Henn; Wolfram Osen; Hanswalt 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 146 KB 👁 1 views

Expression of human papillomavirus type 16 (HPV 16) fusion proteins LI deltaCE7(1-55) and LI deltaCE7(1-60) (carboxy-terminal deletion of LI replaced by 55 or 60 amino-terminal amino acids of E7) leads to formation of chimeric papillomavirus-like particles (CVLPs). After "infection" of cells by CVLP