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Immunization with an HPV-16 L1-based chimeric virus-like particle containing HPV-16 E6 and E7 epitopes elicits long-lasting prophylactic and therapeutic efficacy in an HPV-16 tumor mice model

✍ Scribed by Monroy-García, Alberto; Gómez-Lim, Miguel Angel; Weiss-Steider, Benny; Hernández-Montes, Jorge; Huerta-Yepez, Sara; Rangel-Santiago, Jesús F.; Santiago-Osorio, Edelmiro; Mora García, María de Lourdes

Book ID
120995254
Publisher
Springer Vienna
Year
2013
Tongue
English
Weight
709 KB
Volume
159
Category
Article
ISSN
1432-8798

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Immunization with an HPV-16 L1-based chi
Immunization with an HPV-16 L1-based chimeric virus-like particle containing HPV-16 E6 and E7 epitopes elicits long-lasting prophylactic and therapeutic efficacy in an HPV-16 tumor mice model
✍ Monroy-García, Alberto; Gómez-Lim, Miguel Angel; Weiss-Steider, Benny; Hernán 📂 Article 📅 2013 🏛 Springer Vienna 🌐 English ⚖ 709 KB

HPV L1-based virus-like particles vaccines (VLPs) efficiently induce temporary prophylactic activity through the induction of neutralizing antibodies; however, VLPs that can provide prophylactic as well as therapeutic properties for longer periods of time are needed. For this purpose, we generated a