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Human Papillomavirus L1L2-E7 Virus-Like Particles Partially Mature Human Dendritic Cells and Elicit E7-Specific T-Helper Responses From Patients With Cervical Intraepithelial Neoplasia or Cervical Cancer In Vitro

✍ Scribed by Dominic E. Warrino; Walter C. Olson; Meera I. Scarrow; Lori J. D’Ambrosio-Brennan; Richard S. Guido; Diane M. Da Silva; W. Martin Kast; Walter J. Storkus

Book ID: 116530749
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 230 KB
Volume: 66
Category: Article
ISSN: 0198-8859
DOI: 10.1016/j.humimm.2005.04.006

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## Abstract The E6 and E7 proteins encoded by human papillomaviruses (HPV) are prime targets for therapeutic vaccine development. Ninety‐five women with HPV 52 infection (33 transient infections, 17 cervical intraepithelial neoplasia grade II, 15 cervical intraepithelial neoplasia grade III, and 30