Experimental studies have shown that the fidelity of DNA replication can be affected by the concentrations of free deoxyribonucleotides present in the cell. Replication of mammalian chromosomes is achieved using pools of newly-synthesized deoxyribonucleotides which fluctuate during the cell cycle. S
β¦ LIBER β¦
Human mutation rate associated with DNA replication timing
β Scribed by Stamatoyannopoulos, John A; Adzhubei, Ivan; Thurman, Robert E; Kryukov, Gregory V; Mirkin, Sergei M; Sunyaev, Shamil R
- Book ID
- 109914436
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 205 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/ng.363
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The mitochondrial DNA (mtDNA) of hair follicles was a mild increase in the percentage of the 7,436 was used for studying the genotoxicity of smoking-bp dmtDNA with the increase of the consumption mediated carcinogens. We determined the inci-of cigarettes. No tandem duplication of mtDNA in dences of