Human low-density lipoprotein receptor gene and its regulation
โ Scribed by Wei-Jia Kong; Jingwen Liu; Jian-Dong Jiang
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 252 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0946-2716
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Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada
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