Many colorectal cancers have high levels of cyclo-oxygenase 2 (COX-2), an enzyme that metabolizes the essential fatty acids into prostaglandins. Since the low-density lipoprotein receptor (LDLr) is involved in the uptake of essential fatty acids, we studied the effect of LDL on growth and gene regul
β¦ LIBER β¦
Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2
β Scribed by Yunfei Chen; Millie Hughes-Fulford
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 129 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
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The aim of this study was to identify the proteolytic activity which triggers the transformation of human β£2-macroglobulin (β£2-M) in seminal fluid and its binding to its receptor. METHODS. Measurement of the concentrations of total and transformed β£2-M in seminal fluid was accomplished by ELISA. Zym