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Human exposure to styrene

โœ Scribed by M. Guillemin; D. Bauer


Publisher
Springer-Verlag
Year
1976
Tongue
English
Weight
328 KB
Volume
37
Category
Article
ISSN
0340-0131

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โœฆ Synopsis


A simple and specific method for the quantitative gaschromatographic (GC) analysis of mandelic and phenylglyoxylic acid (MA and PGA), human urinary styrene metabolites, is described MA is determined by trimethylsilylation and subsequent GC analysis Because of difficulties involved in the direct determination of PGA due to the lack of quantitative and reproducible derivatization methods, this acid is reduced to MA prior to GC analysis By a double determination with and without reduction both acids can be analyzed quantitatively Both analysis show the same accuracy and precision and can therefore be intercorrelated accurately.


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