We examined 22 cases of renal-cell carcinoma (RCC) for structural alterations of the epidermal growth factor receptor (ECFR) gene and found gene amplification in one case of high-stag+high-grade RCC. Dot blot analysis of the total RNA from tumorous and normal kidney tissues revealed overexpression o
β¦ LIBER β¦
Human epidermal growth factor receptor 2 overexpression and amplification in mucinous tumours of ovary
β Scribed by Cyril B Gilks; Jessica McAlpine
- Book ID
- 110092820
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 45 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0309-0167
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## Abstract Esophageal carcinomas from 24 patients, most of whom were smokers and consumed alcoholic beverages daily, were analyzed for mutations in exons 5β8 of the __p53__ tumor suppressor gene. Mutations were identified by polymerase chain reaction amplification and direct sequencing in 12 of 24