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Overexpression and activation of epidermal growth factor receptor in hemangioblastomas

✍ Scribed by Gregory J. Chen; Matthias A. Karajannis; Elizabeth W. Newcomb; David Zagzag


Publisher
Springer US
Year
2010
Tongue
English
Weight
350 KB
Volume
99
Category
Article
ISSN
0167-594X

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Activation of cells is frequently followed by tyrosine phosphorylation of proteins. To quantify this process, we developed a ratiometric enzyme-linked immunosorbent assay (ELISA) using epidermal growth factor receptors (EGFR) as a model. Microtiter dishes were coated with anti-EGFR monoclonal antibo