Human dendritic cells activate T lymphocytes via a CD40: CD40 ligand-dependent pathway
✍ Scribed by Alexander D. McLellan; Rüdiger V. Sorg; Lisa A. Williams; Derek N. J. Hart
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 801 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
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## Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes To identify the ligand for the B cell-associated antigen CD40, we constructed a chimeric immunoglobulin molecule where the extracellular porti
## Endothelial cells augment the expression of CD40 ligand on newly activated human CD4' T cells through a CD2/LFA-3 signaling pathway Cultured human endothelial cells (EC) increase CD40 ligand expression on polyclonally activated human peripheral blood CD4' helper T cells compared to T cells acti