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Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction

✍ Scribed by Uno Shu; Mamoru Kiniwa; Chang You Wu; Charles Maliszewski; Nadia Vezzio; John Hakimi; Maurice Gately; Guy Delespesse


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
385 KB
Volume
25
Category
Article
ISSN
0014-2980

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Langerhans cells (LC) are professional antigen-presenting cells of dendritic cell (DC) lineage and are critical for the induction of primary immune responses in skin. Following antigenic stimulation, LC migrate to regional lymph nodes and induce antigen-specific activation of T cells. After primary