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Human colonic adenocarcinoma cells

✍ Scribed by Baldwin H. Tom; Lynne P. Rutzky; Milda M. Jakstys; Ryoichi Oyasu; Celia I. Kaye; Barry D. Kahan


Book ID
112895860
Publisher
Society for In Vitro Biology
Year
1976
Tongue
English
Weight
934 KB
Volume
12
Category
Article
ISSN
1475-2689

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Polyethylene glycol (PEG 8000) is a potent cancer chemopreventive agent. This osmotic laxative polymer markedly suppresses colon cancer in rats. To explain the mechanism, we have tested the in vitro effect of PEG on four human cell lines. Two poorly differentiated adenocarcinoma lines (HT29 and COLO