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Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1

โœ Scribed by Cologna, Stephanie M.; Cluzeau, Celine V. M.; Yanjanin, Nicole M.; Blank, Paul S.; Dail, Michelle K.; Siebel, Stephan; Toth, Cynthia L.; Wassif, Christopher A.; Lieberman, Andrew P.; Porter, Forbes D.


Book ID
121691425
Publisher
Springer
Year
2013
Tongue
English
Weight
329 KB
Volume
37
Category
Article
ISSN
0141-8955

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## Abstract Niemannโ€Pick type C1 (NPC1) disease is an autosomalโ€recessive cholesterolโ€storage disorder characterized by liver dysfunction, hepatosplenomegaly, and progressive neurodegeneration. The NPC1 gene is expressed in every tissue of the body, with liver expressing the highest amounts of NPC1