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Hprt activities and RNA phenotypes in 6-thioguanine resistant human T-lymphocytes

✍ Scribed by Ann-Marie Steen; Sigrid Sahlén; Sai-Mei Hou; Bo Lambert


Book ID
113194407
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
517 KB
Volume
286
Category
Article
ISSN
0027-5107

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The incidence of spontaneous 6-thioguanine-resistant (TGr) lymphocytes was studied in the peripheral blood collected from seven Fanconi anemia (FA) patients and five of their heterozygous parents using an autoradiographic or a lymphocyte cloning method. Five of the seven patients showed a significan