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Resistance to 6-thioguanine in spontaneously cycling and in mitogen-stimulated human peripheral lymphocytes

✍ Scribed by H. Amnéus; B. Sjögren; G. Zetterberg

Book ID
113254636
Publisher
Elsevier Science
Year
1984
Weight
233 KB
Volume
139
Category
Article
ISSN
0165-7992

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✍ Vijavalaxmi; E. Wunder; T. M. Schroeder 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 673 KB

The incidence of spontaneous 6-thioguanine-resistant (TGr) lymphocytes was studied in the peripheral blood collected from seven Fanconi anemia (FA) patients and five of their heterozygous parents using an autoradiographic or a lymphocyte cloning method. Five of the seven patients showed a significan