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HPLC-fluorescence assay for measuring mosapride in small volumes of rat plasma

✍ Scribed by Ching-Ling Cheng; Ya-Win Chang; Chen-Hsi Chou

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
348 KB
Volume
24
Category
Article
ISSN
0269-3879

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Validation of a simple HPLC method for a
Validation of a simple HPLC method for assay of haplamine and its metabolites in plasma suitable for pharmacokinetic application in rats
✍ Sompheary Ea; Claude Aubert; Sarah Giacometti; Joseph Ciccolini; Chhan Siv; Hot πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 1 views

## Abstract A simple HPLC method with ultraviolet detection has been developed and validated for the simultaneous determination of haplamine and its metabolites (__trans__/__cis__‐3,4‐dihydroxyhaplamine) in rat. A liquid–liquid extraction was used to extract the compounds from rat plasma. The analy