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How Hepatitis C Virus Counteracts the Interferon Response: The Jury Is Still out on NS5A

✍ Scribed by Seng-Lai Tan; Michael G. Katze


Book ID
112273535
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
247 KB
Volume
284
Category
Article
ISSN
0042-6822

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A striking association has been demonstrated recently between mutations in amino acid residues 2209-2248 of the nonstructural protein 5a (NS5a) region of hepatitis C virus (HCV) and sustained responses to interferon in Japanese patients infected with genotype 1b. Therefore, analysis of this sequence