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How are osteoclasts induced to resorb bone?

โœ Scribed by T.J. Chambers; K. Fuller

Book ID
111400292
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
579 KB
Volume
1240
Category
Article
ISSN
0890-6564

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Interleukin-1 (IL-1) is one of the most potent boneresorbing factors involved in bone loss associated with inflammation. We previously reported that IL-1 prolonged the survival of multinucleated osteoclastlike cells (OCLs) formed in cocultures of murine osteoblasts/stromal cells and bone marrow cell