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Honokiol inhibits HIF pathway and hypoxia-induced expression of histone lysine demethylases

โœ Scribed by Divya Teja Vavilala; V.K. Chaithanya Ponnaluri; Ramya Krishna Vadlapatla; Dhananjay Pal; Ashim K Mitra; Mridul Mukherji


Book ID
116303421
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
785 KB
Volume
422
Category
Article
ISSN
0006-291X

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## Abstract We hypothesized that the neuroprotective role of the standardized Ginkgo biloba (Ginkgoaceae) extract EGb 761 under hypoxic conditions might be associated with its function to increase HIFโ€1 activity based on the fact that oxygen availability is crucial for cellular metabolism and viabi