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l-carnosine and verapamil inhibit hypoxia-induced expression of hypoxia inducible factor (HIF-1 α) in H9c2 cardiomyoblasts

✍ Scribed by Lalita A. Bharadwaj; Gerald F. Davies; Ilungo J. Xavier; Nick Ovsenek


Book ID
118771052
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
660 KB
Volume
45
Category
Article
ISSN
1043-6618

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## Abstract Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia‐inducible factor‐1α (HIF‐1α) in normoxia. In this study, under hypoxic conditions (1% O~2~), we examined the effect of quercetin on the i