## Abstract Neovascularization is involved in beneficial and detrimental processes of tendon pathology. We investigated the influence of repetitive motion on the expression of the most important angiogenic factor, the vascular endothelial growth factor (VEGF) in the 3T3 NIH fibroblast cell line an
Expression of hypoxia-inducible factor-1 alpha (HIF-1α) in patients with the gallbladder carcinoma
✍ Scribed by Erdenebulgan Batmunkh; Mitsuo Shimada; Yuji Morine; Satoru Imura; Hirofumi Kanemura; Yusuke Arakawa; Jun Hanaoka; Mami Kanamoto; Koji Sugimoto; Masaaki Nishi
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 294 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1341-9625
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Aims: To investigate the significance of the hypoxia inducible factors HIF-1a and HIF-2a in gallbladder adenocarcinomas and their relation to angiogenesis and to the expression of VEGF, an angiogenic factor transcriptionally regulated by HIFas. Methods: HIF-1a and 2a expression was assessed immunohi
## Abstract HIF‐1 is reported to transactivate expression of VEGF, which is an important angiogenic factor. To determine whether HIF‐1α plays a role in angiogenesis through its regulation of VEGF, we examined expression of HIF‐1α and its relation to clinicopathologic features, VEGF expression and p