𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Involvement of hypoxia-inducible factor-1 HiF(1α) in IgE-mediated primary human basophil responses

✍ Scribed by Vadim V. Sumbayev; Sally A. Nicholas; Claire L. Streatfield; Bernhard F. Gibbs


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
313 KB
Volume
39
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Flavonoids-induced accumulation of hypox
✍ Sung-Soo Park; Insoo Bae; Yong J. Lee 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB

## Abstract Hypoxia‐inducible factor‐1 alpha (HIF‐1α) is the regulatory subunit of the heterodimeric transcription factor HIF‐1 that is the key regulator of cellular response to low oxygen tension. Under normoxic conditions, HIF‐1α is continuously degraded by the ubiquitin‐proteasome pathway throug

Hypoxia-inducible factor 1 mediates incr
✍ Guoxiang Yuan; Shakil A. Khan; Weibo Luo; Jayasri Nanduri; Gregg L. Semenza; Nan 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 795 KB

## Abstract Sleep‐disordered breathing with recurrent apnea is associated with intermittent hypoxia (IH). Cardiovascular morbidities caused by IH are triggered by increased generation of reactive oxygen species (ROS) by pro‐oxidant enzymes, especially NADPH oxidase‐2 (Nox2). Previous studies showed

Expression of hypoxia-inducible factor-1
✍ Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Seiji Onogawa; Norimasa Matsutani 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 398 KB

## Abstract HIF‐1 is reported to transactivate expression of VEGF, which is an important angiogenic factor. To determine whether HIF‐1α plays a role in angiogenesis through its regulation of VEGF, we examined expression of HIF‐1α and its relation to clinicopathologic features, VEGF expression and p

Overexpression of hypoxia-inducible fact
✍ Jean-Philippe Dales; Stéphane Garcia; Séverine Meunier-Carpentier; Lucile Andrac 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 372 KB

Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor that is involved in tumour growth and metastasis by regulating genes involved in response to hypoxia. HIF-1alpha protein overexpression has been shown in a variety of human cancers, but only 2 studies have documented the prognost

Geldanamycin inhibits migration of gliom
✍ David Zagzag; Motohiro Nomura; David R. Friedlander; CY Blanco; Jean-Pierre Gagn 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB

## Abstract Focal adhesion kinase (FAK) and hypoxia‐inducible factor (HIF‐1α) are both up‐regulated in glioblastoma multiforme (GBMs), particularly in invasive zones. Because FAK may play an important role in the invasion of glioma cells into the surrounding brain, we sought an agent that causes do

Sulforaphane inhibited expression of hyp
✍ Hua Yao; Huiming Wang; Zhuo Zhang; Bing-Hua Jiang; Jia Luo; Xianglin Shi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 399 KB

## Abstract Previous studies show that a number of natural compounds from our diet have anticancer effects. Sulforaphane is the most characterized isothiocyanates (ITCs), which are identified in cruciferous vegetables. Sulforaphane is viewed as a conceptually promising agent in cancer prevention. B