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Homogeneously staining regions in 223 breast carcinomas: cytogenetic and clinicopathological correlations

✍ Scribed by Dutrillaux, B; Bernardino, J; Gerbault-Seureau, M; Zafrani, B; Dericke, Y; Boudou, E; Magdelenat, H


Book ID
109838663
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
789 KB
Volume
78
Category
Article
ISSN
0007-0920

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## Abstract A modified comparative genomic hybridization (mCGH) technique was applied to a series of 17 primary breast carcinomas in which cytogenetic study (CG) demonstrated the presence of homogeneously staining region(s), suggesting the occurrence of DNA amplification. mCGH demonstrated recurren

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A modified comparative genomic hybridization (mCGH) technique was used t o identify and map amplified DNA sequences in six homogeneously staining regions (hsr) from three primary breast carcinomas. Five different chromosomal regions and bands were identified as sites of amplification: 8p I, I7q2 I.