Optically active [m.n.l]propellanones have been prepared by diastereoselective cyclopropanation of homochiral ene ketals derived from 1,4-di-O-benzyl-L-threltol and readily available bicyclic enones. Propellanones are a synthetically useful subset of the structurally and theoretically interesting pr
Homochiral ketals in organic synthesis. Enantioselective preparation of (+)-modhephene
β Scribed by Eugene A. Mash; Shivanand K. Math; Christopher J. Flann
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 226 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Most important was the generality of the separability of diastereomeric @)-methyl lnctyl pyranosides (entries 1,5-9, Table 1) and furanosides (entries 10-12). Note that in entries 5,9,11, and 12, a second stereogenic center in the ring bearing a substituent is stereochemically "linked" t o the chira
A new C-4 chiral building block, that is a tn> (hydroxymethyl)methane derivative where the three equivalent hydroxymethyl groups have been differentiated [(THYM)\*], was prepared with excellent enautioselection, through PPL catalysed monohydrolysis of prochiral diacetate 3.