𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stannylfuranones in synthesis: Highly enantioselective preparation of (+)-hamabiwalactone B

✍ Scribed by Alexandre M.E. Richecoeur; J.B. Sweeney

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
191 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Preparation of (+)-Hamabiwalactone B via
Preparation of (+)-Hamabiwalactone B via Stille Coupling of an Enantiomerically Pure Stannylfuranone
✍ Alexandre M.E. RichecΕ“ur; J.B. Sweeney πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 132 KB

An unambiguous and highly enantioselective total synthesis of the naturally occurring 2(5H)-furanone Hamabiwalactone B has been achieved. The key step was a palladium-catalysed cross coupling ("Stille" coupling) of the previously unreported stannylfuranone 2 with (E)-iodoalkene 3. The enantiomeric p

Studies in the aza-Cope reaction: a form
Studies in the aza-Cope reaction: a formal highly enantioselective synthesis of tryprostatin B
✍ A Sofia Cardoso; Ana M Lobo; Sundaresan Prabhakar * πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 111 KB

The BF 3 -Et 2 O induced rearrangement of N-phthaloyl-1-(3,3-dimethylallyl)-L-tryptophane methyl ester proceeds without significant loss of its optical integrity to provide its 2-(3,3-dimethylallyl) isomer, a key intermediate in the synthesis of tryprostatin B.