✦ LIBER ✦
Enzymes as selective reagents in organic synthesis: Enantioselective preparation of “asymmetrized tris (hydroxymethyl)methane”
✍ Scribed by Giuseppe Guanti; Luca Banfi; Enrica Narisano
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 171 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
A new C-4 chiral building block, that is a tn> (hydroxymethyl)methane derivative where the three equivalent hydroxymethyl groups have been differentiated [(THYM)*],
was prepared with excellent enautioselection, through PPL catalysed monohydrolysis of prochiral diacetate 3.