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Homochiral (1S,2R)-1,2-indandiol from asymmetric reduction of 1,2-indanedione by resting cells of the yeast Trichosporon cutaneum

✍ Scribed by Gelson J.Andrade Conceição; Paulo J.S. Moran; J.Augusto R. Rodrigues

Book ID: 104359972
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 189 KB
Volume: 14
Category: Article
ISSN: 0957-4166
DOI: 10.1016/s0957-4166(03)00487-7

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✦ Synopsis

A concise highly diastereo-and enantioselective preparation of homochiral (1S,2R)-1,2-indandiol 1 (75% yield, >99% e.e.) by asymmetric reduction of 1,2-indanedione 5 mediated by fresh resting cells of Trichosporon cutaneum CCT 1903 is reported.

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