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Asymmetric direduction of 1,2-indanedione to cis (1S,2R) indanediol by Trichosporon cutaneum MY 1506

✍ Scribed by Sarah Stahl; Norihiro Ikemoto; Anthony King; Randolph Greasham; Michel Chartrain


Book ID
114398757
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
618 KB
Volume
88
Category
Article
ISSN
1389-1723

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Homochiral (1S,2R)-1,2-indandiol from as
✍ Gelson J.Andrade ConceiΓ§Γ£o; Paulo J.S. Moran; J.Augusto R. Rodrigues πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 189 KB

A concise highly diastereo-and enantioselective preparation of homochiral (1S,2R)-1,2-indandiol 1 (75% yield, >99% e.e.) by asymmetric reduction of 1,2-indanedione 5 mediated by fresh resting cells of Trichosporon cutaneum CCT 1903 is reported.