Homochiral (1S,2R)-1,2-indandiol from as
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Gelson J.Andrade ConceiΓ§Γ£o; Paulo J.S. Moran; J.Augusto R. Rodrigues
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Article
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2003
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Elsevier Science
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English
β 189 KB
A concise highly diastereo-and enantioselective preparation of homochiral (1S,2R)-1,2-indandiol 1 (75% yield, >99% e.e.) by asymmetric reduction of 1,2-indanedione 5 mediated by fresh resting cells of Trichosporon cutaneum CCT 1903 is reported.