Homocarnosine in the cerebrospinal fluid of patients with Huntington's disease
✍ Scribed by Böhlen, Peter; Tell, Guy; Schechter, Paul J.; Agid, Jan Koch-weser Yves; Coquillat, Gilles; Chazot, Guy; Fischer, Catherine
- Book ID
- 122556230
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 517 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0361-9230
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📜 SIMILAR VOLUMES
Lumbar cerebrospinal fluid (CSF) choline (CH) levels were measured in patients with Huntington's chorea (n = 14). This group was found not to differ significantly from normal controls (n = 13). The values for lumbar CSF Ch levels in the normal subjects were comparable with previously reported values
The caudate nucleus has the highest acetylcholinesterase (AChE) activity in the brain and it has been shown that autopsied brain tissue of patients with Huntington's disease (HD) have reduced levels of acetylcholine. Because of these findings, the cholinergic function in HD was studied by measuring