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The cerebrospinal fluid choline levels in patients with Huntington's chorea

✍ Scribed by S. Consolo; H. Ladinsky; S. Bianchi; T. Caraceni

Publisher: Springer-Verlag
Year: 1977
Tongue: English
Weight: 308 KB
Volume: 223
Category: Article
ISSN: 1433-8491
DOI: 10.1007/bf00342343

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✦ Synopsis

Lumbar cerebrospinal fluid (CSF) choline (CH) levels were measured in patients with Huntington's chorea (n = 14). This group was found not to differ significantly from normal controls (n = 13). The values for lumbar CSF Ch levels in the normal subjects were comparable with previously reported values. Of the choreic patients, seven were put on haloperidol treatment (4--6 mg daily). The CSF choline level remained unchanged with this treatment after 20 days. CSF cholinesterase activity was measured in the control and choreic group. The results were not significantly different.

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