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hMLHl and hMSH2 somatic inactivation mechanisms in sporadic colorectal cancer patients

✍ Scribed by Enikó Kámory; Orsolya Kolacsek; Szabolcs Ottó; Orsolya Csuka

Book ID
105644851
Publisher
Springer Netherlands
Year
2003
Tongue
English
Weight
334 KB
Volume
9
Category
Article
ISSN
1219-4956

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## Abstract The __MutYH__ gene is an adenine‐specific DNA glycosylase that prevents G/T transversions. Germline mutation in this gene causes __MYH__‐associated polyposis (MAP) that predispose to hereditary colorectal cancer (CRC). This study describes for the first time the association of the __Mut