HLA–DPB1*0301 is a Major Risk Factor for Rheumatoid Factor–Negative Adult Rheumatoid Arthritis
✍ Scribed by Xiaojiang Gao; Marcelo Fernandez-Vina; Nancy J. Olsen; Theodore Pincus; Peter Stastny
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 295 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
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## Abstract ## Objective The shared epitope (SE)–containing HLA–DRB1 alleles represent the most significant genetic risk factor for rheumatoid arthritis (RA). Recent studies indicate that the SE alleles are associated with only RA that is characterized by the presence of anti–cyclic citrullinated
## Abstract ## Objective To study the frequency of allele A of polymorphism PD‐1.3 of the __PDCD1__ gene in patients with rheumatoid arthritis (RA) and its subsets, based on the presence of rheumatoid factor (RF) and the shared epitope (SE) alleles. ## Methods A total of 1,175 patients with RA a