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HLA expression and function in single and double HLA-B27-transgenic mice

✍ Scribed by F. Kievits; J. Wliffels; W. Lokhorst; W. J. Boerenkamp; P. Ivanyi


Book ID
115094058
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
820 KB
Volume
34
Category
Article
ISSN
0001-2815

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The HLA-B27 transgene was introduced into mice of the B10 background with various H-2 haplotypes. High levels of B27 antigen were detected on the surface of peripheral-blood lymphocytes from mice homozygous for the H-2b, H-2f, H-2s, H-2p, H-2r and H-2k haplotypes. In contrast, cell-surface expressio