𝔖 Bobbio Scriptorium
✦   LIBER   ✦

HLA-B27-transgenic rats, amyloid deposits, and spondyloarthropathies

✍ Scribed by Barbara Uchanska-Ziegler; Andreas Ziegler

Book ID
106292054
Publisher
Springer
Year
2008
Tongue
English
Weight
115 KB
Volume
18
Category
Article
ISSN
1439-7595

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Aberrant innate immune responses in TLR-
Aberrant innate immune responses in TLR-ligand activated HLA-B27 transgenic rat cells
✍ Bi-Feng Qian; Susan L. Tonkonogy; R. Balfour Sartor πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 286 KB

Background: Commensal enteric microbiota initiate and perpetuate immune-mediated colitis in HLA-B27 transgenic (TG) rats but not wildtype (non-TG) littermates. However, the role of the innate immune response to bacterial components has not been established. ## Methods: We examined responses induce

CD4+ T lymphocytes mediate colitis in HL
CD4+ T lymphocytes mediate colitis in HLA-B27 transgenic rats monoassociated with nonpathogenic Bacteroides vulgatus
✍ Frank Hoentjen; Susan L. Tonkonogy; Bi-Feng Qian; Bo Liu; Levinus A. Dieleman; R πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 239 KB

## Background: Hla-b27/beta2 microglobulin transgenic (tg) rats develop spontaneous colitis when raised under specific pathogen-free (spf) conditions or after mono-association with bacteroides vulgatus (b. vulgatus), whereas germ-free tg rats fail to develop intestinal inflammation. spf hla-b27 tg

Hierarchy in the assembly of HLA-B27 and
Hierarchy in the assembly of HLA-B27 and HLA-Cw3 molecules in transgenic mice
✍ Susana Pedrinaci; Julie Hanson; Chella David πŸ“‚ Article πŸ“… 1994 πŸ› Springer-Verlag 🌐 English βš– 841 KB

Cell surface expression of human class I molecules in transgenic mice is dependent upon the available pool of [32-microglobulin ([32m) and the affinity between mouse ~2m and human class I molecules. HLA-B27 and HLA-Cw3 transgenes can be expressed in mouse strains of the H-2 haplotypes b,f, k, and s