HLA-DR and -DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus
โ Scribed by A. Shtauvere; I. Rumba; I. Dzivite; C.B. Sanjeevi
- Book ID
- 110891900
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 333 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0001-2815
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๐ SIMILAR VOLUMES
Three groups of patients with insulin-dependent diabetes mellitus, ascertained by different procedures, were investigated for HLA-A, B, C and D antigens (n = 164), and a subset (n = 93) for HLA-DR. Both HLA-D/DR3 and D/DR4 were strongly positively associated and D/DR2 was negatively associated with
Key words: restriction fragment length polymorphism (RFLP), insulin gene 5' flanking polymorphism (5' FP), insulm gene 6.0-kb probe, Southern blotting, HLA-DBP band patterns, HLA-DQP band patterns, HLA-DR subtypes I NTROD UCTl ON A principal aim of the insulin-dependent diabetes mellitus (IDDM) comp