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HLA-DQB1 Genotypes and Islet Cell Antibodies in the Identification of Siblings at Risk for Insulin-Dependent Diabetes (IDDM) in Finland

✍ Scribed by Helena Reijonen; Paula Vähäsalo; Jukka Karjalainen; Jorma Ilonen; Hans K. Åkerblom; Mikael Knip


Book ID
115621311
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
431 KB
Volume
7
Category
Article
ISSN
0896-8411

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Islet cell and insulin autoantibodies in
✍ Ch. Thivolet; B. Beaufrére; H. Bétuel; L. Gebuhrer; P. Chatelain; A. Durand; J. 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 748 KB

Genetic determination as well as prospective analysis of islet cell autoantibodies and autoantibodies to insulin were conducted in a population of 479 first degree relatives of 174 Type 1 (insulin-dependent) diabetic patients. Analysis of HLA haplotypes within families illustrated the high frequency