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Islet cell autoimmunity and progression to insulin-dependent diabetes mellitus in genetically high- and low-risk siblings of diabetic children

✍ Scribed by J. KARJALAINEN; P. VÁHŚLO; M. KNIP; E. TUOMILEHTO-WOLF; E. VIRTALA; H. K. ÅKERBLOM; THE CHILDHOOD DIABETES IN FINLAND (DiMe) STUDY GROUP


Book ID
108710986
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
888 KB
Volume
26
Category
Article
ISSN
0014-2972

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Islet cell and insulin autoantibodies in
✍ Ch. Thivolet; B. Beaufrére; H. Bétuel; L. Gebuhrer; P. Chatelain; A. Durand; J. 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 748 KB

Genetic determination as well as prospective analysis of islet cell autoantibodies and autoantibodies to insulin were conducted in a population of 479 first degree relatives of 174 Type 1 (insulin-dependent) diabetic patients. Analysis of HLA haplotypes within families illustrated the high frequency