HLA-B27 screening by flow cytometry
β Scribed by Beth Lingenfelter; Thomas C. Fuller; Leah Hartung; Jay Hunter; Carl Wittwer
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 427 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
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## Abstract The study of large groups of individuals (from reactive arthritis epidemics, for example) for epidemiologic and genetic data has been hampered by the techniques by which HLA typing is performed. Microlymphoβcytotoxicity is costly not only in materials but also in the time required to pe
Typing for HLA-B27 by serological methods is routinely performed using the microlymphocytotoxic test (MLCT). Since monoclonal antibodies (MAB) against HLA-B27 are available, flow cytometry (FC), which requires less time than the MLCT has been developed as an alternative technique. The aim of the pre