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HIV-1 protease inhibitors containing statine : Inhibitory potency and antiviral activity

โœ Scribed by J.A. Fehrentz; B. Chomier; E. Bignon; S. Venaud; J.C. Chermann; D. Nisato


Book ID
115765167
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
454 KB
Volume
188
Category
Article
ISSN
0006-291X

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A new hydroxyethylamine class of inhibitors was designed combining features from our clinical candidate, L-735.524, along with small heterocvclic PGaands develoDed in these laboratories. Hiahlv notent inhibitors possessing sub&omolar IC5O's have beenid&ified, whi<h exhibit good antiviral pott& h cel