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History, Applications, and Mechanisms of Deep Brain Stimulation

โœ Scribed by Miocinovic, Svjetlana (author);Somayajula, Suvarchala (author);Chitnis, Shilpa (author);Vitek, Jerrold L. (author)

Book ID
118009182
Publisher
American Medical Association
Year
2013
Tongue
English
Weight
384 KB
Volume
70
Category
Article
ISSN
2168-6149

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High frequency electrical stimulation by means of electrodes implanted into the brain (deep brain stimulation; DBS) recently has become an accepted technique for the treatment of several movement disorders and in particular for Parkinson's disease. Because the effects produced by DBS are similar to

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The mechanism of action of high frequency deep brain stimulation is still unknown. However, in all circumstances and in all target nuclei so far stimulated, the effects mimic those of lesions previously made during thalamotomies, pallidotomies or even subthalamotomies, suggesting an inhibition of at

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There is little debate that deep brain stimulation (DBS) has been an effective tool in the treatment of Parkinson's disease as well as other movement disorders. There remains however, considerable debate concerning the mechanism(s) underlying its beneficial effect. The comparable effect of stimulati