𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Histone deacetylases and transcriptional therapy with their inhibitors

✍ Scribed by Pier Pandolfi

Book ID
105994716
Publisher
Springer
Year
2001
Tongue
English
Weight
55 KB
Volume
48
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Histone deacetylases, transcriptional co
Histone deacetylases, transcriptional control, and cancer
✍ W. Douglas Cress; Edward Seto πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 206 KB πŸ‘ 1 views

A key event in the regulation of eukaryotic gene expression is the posttranslational modification of nucleosomal histones, which converts regions of chromosomes into transcriptionally active or inactive chromatin. The most well studied posttranslational modification of histones is the acetylation of

A shifting paradigm: histone deacetylase
A shifting paradigm: histone deacetylases and transcriptional activation
✍ Catharine L. Smith πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 315 KB πŸ‘ 1 views

## Abstract Transcriptional repression and silencing have been strongly associated with hypoacetylation of histones. Accordingly, histone deacetylases, which remove acetyl groups from histones, have been shown to participate in mechanisms of transcriptional repression. Therefore, current models of