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Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma

✍ Scribed by Ulrike Heider; Martin Kaiser; Jan Sterz; Ivana Zavrski; Christian Jakob; Claudia Fleissner; Jan Eucker; Kurt Possinger; Orhan Sezer


Book ID
114792947
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
365 KB
Volume
76
Category
Article
ISSN
0902-4441

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✍ Yo-ichi Yamashita; Mitsuo Shimada; Norifumi Harimoto; Tatsuya Rikimaru; Ken Shir πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 212 KB πŸ‘ 1 views

## Abstract Remodeling of the chromatin template by inhibition of HDAC activities represents a potential transcriptional therapy for neoplastic disease. A number of HDAC inhibitors that modulate __in vitro__ cell growth and differentiation have been developed. We analyzed the effects of TSA, a spec