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Histone deacetylase inhibitors: a patent review (2009 – 2011)

✍ Scribed by Carafa, Vincenzo; Miceli, Marco; Altucci, Lucia; Nebbioso, Angela


Book ID
120060502
Publisher
Informa plc
Year
2012
Tongue
English
Weight
351 KB
Volume
23
Category
Article
ISSN
1354-3776

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## Abstract Histone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients. The HDAC inh